Dehydrocostus Lactone

CAS No. 477-43-0

Dehydrocostus Lactone( Dehydrocostus Lactone | (-)-Dehydrocostus lactone. )

Catalog No. M18596 CAS No. 477-43-0

Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 58 In Stock
25MG 115 In Stock
50MG 192 In Stock
100MG 295 In Stock
500MG 710 In Stock
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Biological Information

  • Product Name
    Dehydrocostus Lactone
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.
  • Description
    Dehydrocostus Lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ. Dehydrocostus Lactone Suppresses Proliferation of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl-JAK/STAT Signaling Pathways. Dehydrocostus Lactone Inhibits Proliferation, Antiapoptosis, and Invasion of Cervical Cancer Cells Through PI3K/Akt Signaling Pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Dehydrocostus Lactone | (-)-Dehydrocostus lactone.
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    477-43-0
  • Formula Weight
    230.3
  • Molecular Formula
    C15H18O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 62.5 mg/mL; 271.39 mM
  • SMILES
    C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C
  • Chemical Name
    (3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dong GZ, et al. PhytOthers Res. 2015 May;29(5):680-6.
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